File Name: macrolides and ketolides azithromycin clarithromycin telithromycin .zip
The authors declare no financial disclosure.
- Macrolide antibiotics in respiratory diseases. Recommendations of the Polish Expert Group — AD 2015
- Effects of Macrolides and Ketolides on Mycobacterial Infections
- Macrolide Therapy in Chronic Inflammatory Diseases
The macrolides are a class of natural products that consist of a large macrocyclic lactone ring to which one or more deoxy sugars , usually cladinose and desosamine , may be attached.
Macrolide antibiotics in respiratory diseases. Recommendations of the Polish Expert Group — AD 2015
Effects of Macrolides and Ketolides on Mycobacterial Infections
Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability.
Macrolide Therapy in Chronic Inflammatory Diseases
The current state of research, development, and use of macrolides as a treatment option for bacterial infections is the subject of this monograph. Macrolides, whose first representative erythromycin was introduced into the market in the s, have been optimised by various companies into effective, safe, and convenient treatments with overwhelming success. Various compounds, such as azithromycin, clarithromycin, erythromycin, and roxithromycin, are in current effective use for treatment of infections mainly of the respiratory, gastrointestinal, and urogenital tracts and skin and soft tissues.
Author s : Luiz E. DOI : New macrolides, such as clarithromycin and azithromycin, are active agents to Mycobacterium avium complex MAC.
Macrolides are a group of antibiotics with a distinctive macrocyclic lactone ring combined with sugars cladinose, desosamine. The action of macrolides is to block protein synthesis by binding to the subunit of 50S ribosome of bacteria. Prototype macrolide was erythromycin, which came into clinical practice in the 50s of the 20th century.